Posts Tagged ‘DMD’

How to Live with Muscular Dystrophy

April 23rd, 2009

The following article has been submitted by
Ayush Muscular Dystrophy Society India

Muscular dystrophy is a bundle of severe debilitating conditions in which the muscles that control movement progressively weaken. In some forms of this disease, the heart and other organs are also affected.  Currently there is no cure for any form of muscular dystrophy. Some modern medicines, ayurvedic remedies and therapies can slow the course of the disease.  This article introduces with a main thrust complementary program of care through research on Muscular dystrophy with a focus on Ayurvedic Panch Karma and Yogic approach of treatment. The Ayurvedic Mamsagni Rasayana herbs have shown definite protective influence and longer survival upon muscular dystrophy.

Muscular dystrophies are a group of more than 20 different genetic neuromuscular disorders, some more debilitating than others. The most common, Duchenne muscular dystrophy (DMD) affects 1 in 3500 boys. There is a problem in the chromosome that codes for a protein called dystrophin which maintains the integrity of the muscle cell wall. Eventually irreversible destruction of the muscle cells occurs. In early school years, it may just seem that DMD boys are slower and clumsier than their peers. The disease progresses such that the majority will be wheelchair bound by 10-14 years.

Muscular dystrophies are inherited. Each disease is transmitted by a different genetic trait. DMD is inherited in an X-linked recessive transmission. That means that females may be carriers but do not have any debilitating symptoms. A female carrier has a 50% chance of transmitting the faulty gene onto her children. There is no  satisfactory treatment in any system of medicine. It is a progressive muscle-wasting disease due to a mutation in the dystrophin gene and the consequential protein deficiency in muscle. It results in chronic inflammation and severe skeletal muscle degeneration. How the lack of the sarcolemma protein dystrophin gives rise to the final disease status is still not clear.

The genetic disease conditions are diagnosed through genetic testing, a physical exam, a family medical history, and some specific tests. These might include: A muscle biopsy (the removal and examination of a small sample of muscle tissue)

  • DNA (genetic) testing
  • Electromyography or nerve conduction tests (which use electrodes to test muscle and/or nerve function)
  • Blood enzyme tests (which may reveal muscle damage)

For DMD and BMD, muscle biopsy may show whether dystrophin protein is missing or abnormal, and DNA Test is used to analyze the condition of the related gene.
» Read more: How to Live with Muscular Dystrophy

Fight Muscular Disability With Ayurveda: DMD, BMD and LGMD

April 22nd, 2009

Bhilai (Ayush Samiti): – Mamsagni Rasayana and modified Til-Mash Pinda Swedana may delay muscle damage associated with DMD, BMD and LGMD, according to research reported in Seminar on Neuro-Muscular Diseases organized recently by AMDS India in Bhilai. Muscular dystrophy is not a single disease but a group of hereditary muscle destroying disorders, vary in their inheritance pattern, age of onset, initial muscle attacked and rate of progression. It is no incurable condition; rather it is a genetic problem for which no satisfactory treatments have yet been found in any system of medicine. Duchenne’s muscular dystrophy is associated with severe, progressive muscle weakness and typically leads to death between the ages of 20 and 35 years. Absence of dystrophin causes the weakness and muscle wasting of Duchenne muscular dystrophy, as well as cardio-myopathies and cardiac failure, Dr. Mukesh Jain noted in correspondence with Ayush Samiti.

Duchenne muscular dystrophy (DMD) affects about 1 in 3,500 males. Becker muscular dystrophy (BMD) affects about 1 in 30,000 males although this may be an underestimate due to its variable severity. DMD and BMD are due to different changes in the dystrophin gene, which contains information for a protein that is important for muscle cells to work properly. This gene is located on the X chromosome.

Have you ever considered using Ayurveda and Yoga based techniques for management of complex diseases like muscular dystrophy? We wish to inform you of the promising results that we have achieved at our special clinic in treating the debilitating effects of muscular dystrophy using Ayurveda and Yoga based techniques. The Muscular Dystrophy programme being run at Sanjivani Hospital Bhilai, focuses on – (i) Reducing weight, (ii) Improving muscle tone and functional ability in patients using specific Panchkarma procedures, specially developed Rasayana supplement, and yogic support.

» Read more: Fight Muscular Disability With Ayurveda: DMD, BMD and LGMD